Biological Underpinnings of Chronic Fatigue?

A recent synopsis in Nature describes a study showing that immune cells in patients with chronic fatigue behave differently in vitro to those in healthy controls.[1] This suggests that the disease is not psychosomatic, argues the synopsis. That is not just out of date thinking, it is long out of date – the inter-relationship between mind and body has been known for over a century. The article suggests that gut bacteria may differ in chronic fatigue syndrome. If this hypothesis is confirmed then maybe the condition originates somatically and affects the brain, not the other way around. We develop this idea further in the next exciting instalment of your news blog.

— Richard Lilford, CLAHRC WM Director


  1. Maxmen A. Biological underpinnings of chronic fatigue emerge. Nature. 2017; 543: 602.

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